This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy. Women with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.
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Number of carotid plaques
Timeframe: At study visit (≥3 years postpartum)
Hemoglobin A1c (HbA1c)
Timeframe: At study visit (≥3 years postpartum)
Lipid profile
Timeframe: At study visit (≥3 years postpartum)
Blood pressure
Timeframe: At study visit (≥3 years postpartum)
Body mass index
Timeframe: At study visit (≥3 years postpartum)
Diabetic-related chronic microvascular complications
Timeframe: From the last pregnancy to the study visit (≥3 years postpartum)
Incident cardiovascular events
Timeframe: From last pregnancy to study visit (minimum 3 years)