CompletedNot Applicable

A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma

China169 participantsStarted 2018-01-01

Plain-language summary

The aim of this observational study was to understand the prognostic imaging of the degree of intratumoral fibrosis and intratumoral α-SMA levels in patients with intrahepatic cholangiocarcinoma (ICC). The main questions it aims to answer are: Whether the degree of intratumoral fibrosis and the level of intratumoral α-SMA affect the overall survival and progression-free survival of ICC patients. Participants will be surveyed for survival and tumor recurrence up to 5 years after surgery.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who underwent radical resection of liver tumors in our center and obtained surgical specimens; * ICC was diagnosed by postoperative pathology Exclusion Criteria: * Patients had received radiotherapy, chemotherapy, intervention and other treatments for liver tumors before surgery * The tumor sections could not be obtained due to the loss of wax blocks or most of the defects of pathological specimens * No upper abdominal Gd-EOB-DTPA-enhanced MRI examination in our center within one month before surgery * Poor image quality or incomplete image data

What they're measuring

Treatment Effects

Timeframe: From the time of the patient's surgery to the end of the 5-year follow-up

Trial details

NCT IDNCT07479264

SponsorFirst Affiliated Hospital, Sun Yat-Sen University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-01-17

View on ClinicalTrials.gov More Intrahepatic Cholangiocarcinoma (Icc) trials