CompletedNot Applicable

Effect of Two Different Fluid Treatment Regimens on Ultrasonographic Upper Airway Measurements

Turkey (Türkiye)145 participantsStarted 2023-03-01

Plain-language summary

The goal of this randomized controlled double blinded study is to compare the effect of the type of fluid theraphy on ultrasonographic upper airway measurements for spinal surgery in prone position longer than two hours. The main question it aims to answer is how do goal directed fluid theraphy and standard fluid theraphy effect ultrasonographic upper airway measurements. Participants will be American Society of Anesthesiology (ASA) physical status I and II, between 18- 65 ages. Resarchers will compare goal-directed fluid therapy with standard fluid theraphy to see if upper airway ultrasonography measurements differs between the groups.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-65 years old * ASA (American Association of Anesthesiologists) I and II * Elective spine surgery in prone position * Surgeries longer than 120 minutes Exclusion Criteria: * Chronic pulmonary disease * Renal dysfunction (glomerular filtration rate \<30 ml/kg/min) * Congestive heart failure (ejection fraction ≤35%) * Serious arrhythmias * Peripheral vascular disease * Pregnance * Patients with coagulation disorders * Patients who need more than 2 intubation attempts * Prior cervical surgery * Patients with neck extension limitation * Upper respiratory tract infection in the last 3 weeks * Patients expected to have a difficult airway (Mallampati III-IV) * Patients with a body mass index (BMI) of 35 and above * Patient's refusal

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Epiglottic thickness

Timeframe: immediately before surgery

Tongue thickness

Timeframe: immediately before surgery

Trial details

NCT IDNCT07477392

SponsorBozyaka Training and Research Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-01

View on ClinicalTrials.gov More Goal-directed Fluid Theraphy trials