Active — Not RecruitingNot Applicable

Evaluating the Efficacy of Voice Therapy for Neurogenic Voice Disorders

United States40 participantsStarted 2024-06-04

Plain-language summary

The goal of this study is to evaluate the efficacy of voice therapy for neurogenic voice disorders. The main questions are: Does voice therapy improve patient-reported quality of life in speakers with neurogenic voice disorders? Does voice therapy improve listener perception of voice in speakers with neurogenic voice disorders? Does voice therapy improve acoustical analyses of voice in speakers with neurogenic voice disorders? Does voice therapy improve physiologic function in speakers with neurogenic voice disorders?

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of essential tremor by a physician * Self-reported, physician-identified, or speech-language pathologist-identified vocal tremor * Ability to speak and read English * Ability to follow instructions and pay attention to tasks Exclusion Criteria: * History of surgery on the oral cavity, larynx, pharynx, or respiratory system that currently affects speech or voice * Current respiratory disorder unrelated to essential tremor that affects speech or voice * Score 20 points or below on the Mini-Mental Status Examination

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Patient-reported outcome measures

Timeframe: Participants will complete ratings during the treatment phase at the beginning of the first treatment session and at the end of the last treatment session.

Auditory-perceptual ratings

Timeframe: Listeners will rate samples from all study phases within two years after all data have been collected from all study participants.

Acoustical analyses - extent of modulation

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.

Acoustical analyses - modulation rate

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.

Acoustical analyses - cepstral peak prominence

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.

Trial details

NCT IDNCT07474740

SponsorUniversity of Texas at Austin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06-04

View on ClinicalTrials.gov More Speakers With Neurogenic Voice Disorders trials

Plain-language summary

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Patient-reported outcome measures

Timeframe: Participants will complete ratings during the treatment phase at the beginning of the first treatment session and at the end of the last treatment session.

Auditory-perceptual ratings

Timeframe: Listeners will rate samples from all study phases within two years after all data have been collected from all study participants.

Acoustical analyses - extent of modulation

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.

Acoustical analyses - modulation rate

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.

Acoustical analyses - cepstral peak prominence

Timeframe: Audio recordings from all study phases will be analyzed within 2 years after completing data collection.