RecruitingPhase 4

Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section

Egypt150 participantsStarted 2025-09-20

Plain-language summary

To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

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Exclusion criteria

✕. Cases of urgent or emergent CS.
✕. Abnormal vaginal secretion (bad smelling yellowish secretion, whitish cheesy discharge with pruritus, bloody discharge; etc…).
✕. Women with medical disorders such as pre-gestational diabetes, anemia, hypertension, preeclampsia, or immunosuppressant pregnant women.
✕. Women who had a skin infection adjacent to the operative site.
✕. Allergy to topical povidone-iodine or clindamycin
✕. Feverish patients or history of premature rupture of membranes or with placenta previa.
✕. patients lost during follow-up were excluded from the final analysis.

What they're measuring

Wound infection (surgical site infection SSI)

Timeframe: 3 weeks

Trial details

NCT IDNCT07474194

SponsorBeni-Suef University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-30

Contact for this trial

Sara Abdallah Salem, MD

201272842226 sara.abdalla@med.bsu.edu.eg

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