CompletedNot Applicable

Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic Scalpel

Pakistan158 participantsStarted 2020-02-01

Plain-language summary

This randomized controlled trial compares the operative outcomes of clipless laparoscopic cholecystectomy using a harmonic scalpel (HS) versus conventional clip-based laparoscopic cholecystectomy (CLC) in patients with gallstone disease. The primary goals are to determine if the clipless HS technique reduces operative time and intraoperative blood loss. Secondary outcomes include the length of postoperative hospital stay and the rate of port-site infections.

Who can participate

Age range20 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 20-70 years. * Diagnosis of gallstone disease confined to the gallbladder. * Scheduled for elective laparoscopic cholecystectomy. Exclusion Criteria: * ASA (American Society of Anesthesiologists) physical status class III or IV. * Renal dysfunction (serum creatinine \> 2.0 mg/dL). * Coagulopathy (PT \>1 s above control, aPTT \>33 s, INR \>1.5). * Pregnancy. * Presence of common bile duct stones. * Previous upper abdominal surgery or laparotomy.

What they're measuring

Operative Time in minutes

Timeframe: 120 minutes

Intraoperative Blood Loss in ml

Timeframe: 120 minutes

Trial details

NCT IDNCT07473388

SponsorServices Hospital, Lahore

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-06-15

View on ClinicalTrials.gov More Cholecystectomy, Laparoscopic trials