Efficacy of a Combined Oral and Topical Collagen Regimen Compared to Topical Collagen or Oral Col… (NCT07473037) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Efficacy of a Combined Oral and Topical Collagen Regimen Compared to Topical Collagen or Oral Collagen Regimens in Women With Skin Ageing Signs
165 participantsStarted 2026-03-15
Plain-language summary
This clinical study is conducted at one study site and in 165 women with visible signs of skin aging. It compares after 13 weeks the benefit of a combined oral collagen supplement and topical collagen serum regimen compared with oral collagen alone and topical collagen serum alone in reducing in women presenting visible signs of skin ageing .
Who can participate
Age range
45 Years – 60 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participant having signed an Informed Consent Form (ICF) before any trial related activity is carried out;
* Female participant;
* Participant with a Fitzpatrick skin type I to III;
* Participant aged 45 to 60 years inclusive at the time of signing the ICF;
* Participant with a BMI ≥20 and \< 29 kg/m²;
* Participant presenting:
* Cheek firmness score ≥3 and ≤6 on the 10-point scale;
* Crow's feet wrinkle score ≥2 and ≤4 on the L'Oréal Atlas;
* Global facial wrinkle score ≥3 and ≤6 on the 10-point scale.
* Female participant of childbearing potential must use one of the reliable methods of contraception during the investigation and agree not to change it during the study;
A woman is considered of childbearing potential unless she is:
* Postmenopausal for at least 12 months prior to screening visit;
* Without uterus and/or both ovaries;
* Has been surgically sterile for at least 6 months prior to Screening visit.
* Participant must agree to use only the designated products
* Participant willing and able to comply with all study procedures, lifestyle and dietary restrictions, and complete the entire study period
* Participant affiliated to a health social security system (according to French Law).
Exclusion Criteria:
* Participant who is pregnant or who is breast feeding;
* Participant receiving hormone replacement therapy (HRT).
* Participant who smokes more than two cigarettes per week;
* Participant whose alcohol intake exceeds 2 drinks per week;
* …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Crow's feet score on the L'Oreal Skin Atlas (Caucasian type) scale ranging from 0=no wrinkles to 6=very deep severe wrinkles