In recent studies, it has been reported that the renal resistance index is effective in detecting sepsis-related acute renal failure (SA-AKI) in the early period. Similarly, urinary biomarkers \[TIMP-2\]\*\[IGFBP-7\], released in response to tubular epithelial cell stress, have been reported to indicate the presence of acute renal injury (AKI) early on, before functional loss occurs (increased creatinine). This observational study aims to evaluate the renal resistance index and urinary biomarker variation in patients diagnosed with sepsis and to investigate their usefulness in the early detection of renal dysfunction that may develop after sepsis.
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Renal resistance index (RRI)
Timeframe: Immediately after sepsis diagnosis (T0, baseline, first measurement)
Renal resistance index (RRI)
Timeframe: 24 hours after sepsis diagnosis (T24, second measurement)
Renal resistance index (RRI)
Timeframe: 48 hours after sepsis diagnosis (T48, third measurement)
Urine [TIMP-2]•[IGFBP-7] biomarker
Timeframe: Immediately after diagnosis of sepsis (T0)
Urine [TIMP-2]•[IGFBP-7] biomarker
Timeframe: 24 hours after diagnosis of sepsis (T24)