RecruitingNot Applicable

Characterization of Renal Microvascular Alterations in Patients With Active Urinary Sediment and/or Proteinuria Using Ultrasound Localization Microscopy

Germany30 participantsStarted 2025-09-18

Plain-language summary

The goal of this study is the non-invasive visualization and quantification of renal microvascular dynamics in adult kidneys with proteinuria and/or active sediment.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * Evidence of active urinary sediment and/or proteinuria \>1 g/g creatinine * Indication for kidney biopsy as part of study-independent diagnostics * Written informed consent Exclusion Criteria: * Known allergic disposition to SonoVue® * Contraindication to the use of SonoVue® * Pregnancy * Breastfeeding mothers

What they're measuring

CEUS Time intensity curves

Timeframe: baseline and up to 10 weeks after baseline

CEUS Measurement1

Timeframe: baseline and up to 10 weeks after baseline

CEUS Measurement2