CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal Stenosis (NCT07469020) | Clinical Trial Compass
RecruitingNot Applicable
CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal Stenosis
France49 participantsStarted 2026-08
Plain-language summary
The goal of this interventional study is to evaluate the rate of existing lower limb peripheral artery disease (PAD) in patients with surgically lumbar spinal stenosis (LSS). PAD and LSS can present similar symptoms and it can be difficult to diagnose PAD using conventional methods, depending on the location of the arterial disease. The main questions it aims to answer are :
* What's the prevalence of PAD in LSS patients?
* Which exam among routine tools is the most accurate to diagnose PAD in this population? Around their surgery for LSS (a few weeks before or after), participants will be included in a vascular medicine service. After checking of eligibility criteria, they will undergo a contrast-enhanced CT scan for the diagnosis of PAD and various routine diagnostic tests: Doppler ultrasound, treadmill tests, pressure index, pulse palpation.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Presenting with a lumbar spinal stenosis with surgical indication, either unoperated or operated on less than 3 months ago
* Affiliated with a social security scheme
* Having received oral and written information about the protocol and having signed a written consent form to participate in this research.
Exclusion Criteria:
* emergency surgical care
* Contraindication to contrast enhanced CT scan
* Stroke or myocardial infarction (MI) within the last 3 months
* Known severe or poorly tolerated arrhythmia
* Known severe or symptomatic left ventricular outflow obstruction
* Decompensated heart failure
* History within the last 3 months of venous thromboembolic disease, myopericarditis, endocarditis, aortic dissection or intracardiac thrombus
* Severe uncontrolled hypertension (BP \> 200/110 mmHg)
* Inability to walk on the treadmill
* Major lower limb amputation
* Adult subject to legal protection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of patients with PAD identified during the contrast enhanced CT scan