CompletedNot Applicable

Effect of the MindUP Program on Depression, Anxiety, and Stress in Pakistani Orphan Adolescents

Pakistan61 participantsStarted 2024-06-08

Plain-language summary

This study evaluates the effectiveness of the MindUP mindfulness-based program in reducing depression, anxiety, and stress among orphan adolescents in Pakistan. Adolescents living in orphan care institutions often experience significant psychological distress due to early life adversity, loss of parental support, and institutional living conditions. A school-based quasi-experimental design was used to examine whether participation in the MindUP program improves mental health outcomes among orphan adolescents. Participants were adolescents residing in orphanages in Pakistan who were assigned to either an intervention group receiving the MindUP program or a comparison group receiving routine institutional activities. The MindUP intervention consisted of structured mindfulness and social-emotional learning sessions designed to enhance emotional regulation, attention, and psychological well-being. The program was delivered over several weeks by trained facilitators. Psychological outcomes including depression, anxiety, and stress were measured using standardized self-report scales before and after the intervention. The study aims to determine whether the MindUP program is effective in improving mental health among orphan adolescents in low-resource institutional settings.

Who can participate

Age range

11 Years – 16 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male adolescents aged 11-16 years. Residing in an orphan care institution. Currently enrolled in school (grades 7-8). Able to understand and participate in the MindUP program sessions. Provided assent to participate and permission obtained from the institutional authorities/guardians. Exclusion Criteria: * Adolescents currently receiving psychological or psychiatric treatment. Adolescents with severe cognitive or developmental disorders that would interfere with participation in the intervention. Adolescents who did not complete baseline assessments or were absent for most intervention sessions.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Depression Symptoms (DASS-21 Depression Subscale)

Timeframe: Baseline to Post-Intervention (15 weeks)

Trial details

NCT IDNCT07468994

SponsorQuaid-e-Azam University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-21

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