An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria

Inclusion Criteria: * P. vivax peripheral parasitaemia as determined by microscopy * G6PD normal status (G6PD activity ≥70% of the site specific adjusted male median as determined by the Standard G6PD (SD Bioline, ROK)) * Fever (temperature ≥37.5°C) or history of fever in the preceding 48 hours, * Age ≥5 years * Bodyweight ≥14kg * Living in the study area and willing to be followed-up for six months Exclusion Criteria: * Signs or symptoms of severe malaria, * Anaemia (defined as Hb \<8g/dl) and measured by the Standard G6PD * Pregnant or lactating * Blood transfusion within the preceding four months * Regular or recent use (last month) of tafenoquine, primaquine or dapsone * Known hypersensitivity to any of the study drugs