Combined Mirror Therapy and Soft Robotic Glove for Hand Recovery After Stroke (NCT07467915) | Clinical Trial Compass
RecruitingNot Applicable
Combined Mirror Therapy and Soft Robotic Glove for Hand Recovery After Stroke
Iraq104 participantsStarted 2026-04-08
Plain-language summary
Post-stroke hemiplegia frequently results in impaired upper limb function, which significantly affects independence and quality of life. Various rehabilitation approaches have been developed to improve motor recovery, including mirror therapy and robotic-assisted training. Mirror therapy uses visual feedback to stimulate neural plasticity and enhance motor recovery, while soft robotic gloves assist repetitive hand movements and facilitate functional training.
This randomized controlled trial aims to investigate the effect of combining mirror therapy with a soft robotic glove on hand function recovery in patients with post-stroke hemiplegia. Participants will be randomly assigned to different intervention groups receiving mirror therapy, soft robotic glove training, combined therapy, or conventional rehabilitation.
The primary outcome will assess improvement in upper limb motor function using validated clinical assessment tools. Secondary outcomes will evaluate functional hand performance and activities of daily living. The findings of this study may contribute to improving rehabilitation strategies for stroke survivors and provide evidence for integrating innovative rehabilitation technologies into clinical practice.
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Adults aged 18-70 years with first-ever ischemic or hemorrhagic stroke confirmed by imaging (CT or MRI)
Moderate upper limb motor impairment (Fugl-Meyer Assessment Upper Extremity \[FMA-UE\] score 20-50)
Ability to follow simple instructions (Six-Item Cognitive Impairment Test, 6CIT)
Ability to sit independently for at least 30 minutes
Medically stable and cleared to participate in rehabilitation interventions
Willingness to provide informed consent and adhere to the study protocol
Exclusion Criteria:
Severe upper limb spasticity (Modified Ashworth Scale ≥ 3)
Cognitive or psychiatric disorders interfering with participation
Other neurological or musculoskeletal conditions affecting upper limb function (e.g., Parkinson's disease, multiple sclerosis, fractures)
Prior exposure to intensive Mirror Therapy or Soft Robotic Gloves
Visual impairment that cannot be corrected with glasses or contact lenses
Uncontrolled cardiovascular or other medical conditions that would prevent safe participation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Upper Limb Motor Function (Fugl-Meyer Assessment for Upper Extremity, FMA-UE)
Timeframe: Baseline, 4 weeks during intervention, immediately post-intervention (6 weeks), and 3-month follow-up.
2
Functional Use of Affected Limb (Functional Test of Upper Limb Hemiplegia - Hong Kong, FTHUE-HK)
Timeframe: Baseline, 4 weeks during intervention, immediately post-intervention (6 weeks), and 3-month follow-up