TerminatedNot Applicable

The Effects of Chiropractic Care on Inflammation and Quality of Life in People Living With HIV

Stopped: Recruitment window closed

United States10 participantsStarted 2026-04-11

Plain-language summary

The main aim of this pilot trial is to investigate the feasibility of undertaking a randomized controlled trial involving adults living with HIV. Additionally, this trial will explore potential change differences in self-reported quality of life and blood-derived immune markers between a chiropractic care group and no treatment controls.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18 or older * Medically confirmed HIV diagnosis * Willing to complete online surveys * Willing to share lab results * Willing to be randomized to either once weekly chiropractic care or a no treatment control condition Exclusion Criteria: * Participating in another clinical/behavioral trial related to HIV * Receiving chiropractic care elsewhere * Involved in litigation related to a physical, health-related injury * Has severe osteoporosis or recent spinal fracture

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Proportion of eligible individuals enrolled

Timeframe: From online screen submission to enrollment (up to 2 weeks).

Proportion of trial participants complying with instructions

Timeframe: From enrollment to the end of participation (up to 6 months).

Proportion of chiropractic participants adhering to the care plan

Timeframe: From enrollment to the end of participation (up to 6 months)

Proportion of chiropractic participants retained

Timeframe: From enrollment to the end of the 6 month trial period

Proportion of control participants retained

Timeframe: From enrollment to the end of the 6 month trial period

Trial details

NCT IDNCT07466836

SponsorTyson Perez, DC, PhD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-01

View on ClinicalTrials.gov More Human Immunodeficiency Virus (HIV) trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Proportion of eligible individuals enrolled

Timeframe: From online screen submission to enrollment (up to 2 weeks).

Proportion of trial participants complying with instructions

Timeframe: From enrollment to the end of participation (up to 6 months).

Proportion of chiropractic participants adhering to the care plan

Timeframe: From enrollment to the end of participation (up to 6 months)

Proportion of chiropractic participants retained

Timeframe: From enrollment to the end of the 6 month trial period

Proportion of control participants retained

Timeframe: From enrollment to the end of the 6 month trial period