CompletedPhase 3

Clinical Evaluation of Arthrocentesis, Combination of Platelet-Rich Plasma and Cyclooxygenase Enzyme-2 Inhibitor in Treatment of Temporo-Mandibular Joint Anterior Displacement

Egypt20 participantsStarted 2023-12-01

Plain-language summary

Who can participate

Age range

18 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients aged from 18 to 40 years old. * patients diagnosed with ID of TMJ, suffering from limited mandibular movements, joint pain and clicking. * Patients who are free from any systemic disease and controlled systemic disease (ASA I) (ASA II). * Patients willing to comply with the follow-up schedule and treatment protocol. * both genders are included Exclusion Criteria: * Patients with systemic diseases (ASA III, IV, V). * Patients who have myofascial pain dysfunction syndrome only. * Patients who have previous surgery in TMJ. * Patients who have previous arthrocentesis within 1 year. * Patients who received previous trauma to the joint. * Use of anticoagulants or immunosuppressive medications.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mandibular Movements: measured in millimeters using a ruler or digital caliper.

Timeframe: immediately, one, three and six months postoperatively

pain assessed by visual analogue scale

Timeframe: preoperatively, one, three and six months postoperatively

Joint Clicking: Evaluated using a stethoscope and recorded as either present or absent.

Timeframe: immediately, one, three, six months postoperatively

Trial details

NCT IDNCT07463404

SponsorSuez Canal University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

View on ClinicalTrials.gov More Temporomandibular Joint Internal Derangement trials