CompletedNot Applicable

Effect of Fire-Needle Combined With Regular Acupuncture on Pregnancy Outcome in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization

China100 participantsStarted 2024-07-01

Plain-language summary

This study aims to evaluate whether fire-needle combined with regular acupuncture improves pregnancy outcomes in patients with recurrent implantation failure (RIF), compared to no or regular acupuncture. A retrospective cohort study was conducted at a university-affiliated hospital. One hundred RIF patients undergoing embryo transfer between July 2024 and June 2025 were assigned to three groups: a non-acupuncture group, a regular acupuncture group, and a fire needle combination group (receiving both fire needle and regular acupuncture). Key outcome measures, including the β-hCG positive rate, clinical pregnancy rate (CPR), and miscarriage rate (MR), were compared among the three groups.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * (1)18 ≤age ≤40 years; (2) ≥2 previous failures of high-quality embryo transfer without clinical pregnancy Exclusion Criteria: * (1) preimplantation genetic testing cycles; (2) use of donor oocytes; (3) missing key data on treatment or outcome

What they're measuring

β-hCG-positive pregnancy

Timeframe: 1 year

Clinical pregnancy

Timeframe: 1 year

Miscarriage

Timeframe: 1 year

Trial details

NCT IDNCT07462754

SponsorHuazhong University of Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Implantation Failure trials