RecruitingNot Applicable

Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection

China15 participantsStarted 2026-03-25

Plain-language summary

This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
✓. Splenomegaly with secondary hypersplenism
✓. Bleeding portal hypertension
✓. No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT
✓. Informed consent to participate in the study

Exclusion criteria

✕. Delayed gastric emptying
✕. Diarrhea
✕. Hepatocellular carcinoma or any other malignancy,
✕. Hypercoagulable state other than the liver disease related
✕. DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.
✕. Child - Pugh C
✕. Recent peptic ulcer disease
✕. History of Hemorrhagic stroke

What they're measuring

Incidence of Postoperative Diarrhea

Timeframe: 3 months

Incidence of Delayed Gastric Emptying

Timeframe: 3 months

Trial details

NCT IDNCT07462091

SponsorNorthern Jiangsu People's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-31

Contact for this trial

Guo-Qing Jiang, MD

+86-514-87373272 jgqing2003@hotmail.com

View on ClinicalTrials.gov More Cirrhosis trials