Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1. 1This trial focuses on lifestyle interventions — things like exercise, diet, or sleep changes — rather than medication. Could a lifestyle-based approach actually help with both my depressive symptoms and the cognitive problems like memory, attention, and processing speed that sometimes come with depression?
2. 2The trial is measuring executive functioning and processing speed as primary outcomes alongside depressive symptoms — does my current level of cognitive difficulty make me a good candidate to discuss this kind of study with you, or would treating my depression with standard medication first be a better starting point?
3. 3Since this trial is listed as Phase NA, which typically means it's not testing a drug but rather a behavioral or lifestyle program, what do we know so far about the safety and effectiveness of this type of intervention for people in my situation?
4. 4This study seems to involve multiple outcome measures over time, which might mean regular assessments and follow-up visits — how demanding would participation likely be on my schedule, and is that realistic given where I am right now with my depression?
5. 5Are there standard treatments for major depressive disorder that I should consider trying before or alongside exploring this trial, especially given that the trial is still actively recruiting and results aren't yet known?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.