Not Yet RecruitingNot Applicable

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

United States1,251 participantsStarted 2026-10-01

Plain-language summary

This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school students in real-world classrooms. If successful, E-invite Only VR has the potential to prevent adolescents from experiencing a multitude of poor health outcomes related to nicotine vaping, including cancer.

Who can participate

Age range11 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Enrolled in the 8th grade in one of the 20 partner middle schools (8 in Connecticut, 12 in Massachusetts). * Willing to participate in a VR videogame for approximately 45 minutes per session, accumulating 2-2.5 hours of total gameplay across multiple class periods. * Able to provide assent and obtain parental/guardian consent before participating in the study. Exclusion Criteria * Students not enrolled in 8th grade at one of the participating schools. * Students who are unwilling or unable to participate in VR gameplay for the required duration. * Students who cannot provide assent or do not have parental/guardian consent to participate .

What they're measuring

Number of participants E-cigarette Initiation

Timeframe: 3, 6, and 12 months

Trial details

NCT IDNCT07460622

SponsorYale University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06

Contact for this trial

Kimberly Hieftje D Associate Professor of Pediatrics, PhD

12037375595 kimberly.hieftje@yale.edu

View on ClinicalTrials.gov More E-cigarette Use/Vaping Prevention trials