Chemotherapy-induced diarrhea (CID) is common in patients with gastrointestinal cancer. We evaluated whether the concentrated phytodietary compound (hereafter referred to as CPC) as a nutritional adjuvant to routine anti-diarrheal treatment, acts to alleviate CID in a phase II open-label, single-arm study.
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clinical cure rate of diarrhea
Timeframe: During the first 7 days after CPC administration, record daily the number of bowel movements, stool consistency, gastrointestinal symptoms, BSS score, and the amount of antidiarrheal medications used, such as loperamide and montmorillonite powder.
7-day clinical cure rate
Timeframe: Clinical cure of diarrhea was defined as two consecutive normal solid stool movements or no stool movements within 12 hours after CPC administration.