CompletedNot Applicable

The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery

Turkey (Türkiye)60 participantsStarted 2023-12-06

Plain-language summary

This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator. The study aims to determine if the volume of local anesthetic applied to the epidural space during total knee replacement surgery leads to transient increases in ONSD compared to spinal anesthesia. Participants are randomized into two groups to receive either epidural or spinal anesthesia, and their ONSD measurements are tracked before, during, and after the surgery.

Who can participate

Age range18 Years – 75 Years

SexALL

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Inclusion Criteria: aged 18-75 years with ASA I-III risk group who were scheduled for total knee replacement and volunteered to participate. Exclusion Criteria: Patients with contraindications to regional anesthesia, hypersensitivity to the drugs used, pregnancy, current or past ocular disease/operation history, orbital trauma, optic nerve pathology, glaucoma history; increased intracranial pressure, pseudotumor cerebri, coagulopathy and local infection; and those who refused to participate were excluded.

What they're measuring

Optic Nerve Sheath Diameter (ONSD) Changes

Timeframe: Baseline (T0), 10 minutes after anesthesia (T1), 40 minutes after tourniquet removal (T2), and 24 hours postoperatively (T3).

Trial details

NCT IDNCT07458321

SponsorBursa City Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-01-06

View on ClinicalTrials.gov More Total Knee Replacement trials