HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke (NCT07456956) | Clinical Trial Compass
RecruitingNot Applicable
HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke
Turkey (Türkiye)32 participantsStarted 2026-03-02
Plain-language summary
The aim of this study is to investigate the effect of post-stroke sarcopenia on prognosis and clinical outcomes in patients with ischemic stroke and to compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MCIT) exercise programs on muscle mass, as well as on functional capacity, quality of life, and clinical outcomes.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* First-ever stroke.
* Age 18 years or older.
* Diagnosis of ischemic stroke.
* Stroke duration between 1-6 months (subacute phase).
* Modified Rankin Scale score \< 3.
* Mini-Mental State Examination (MMSE) score ≥ 24.
* Brunnstrom lower extremity motor stage between Stage III-V.
* Lower extremity functional capacity sufficient to allow exercise participation (able to ambulate at least with an assistive device).
* Lower extremity spasticity ≤ 2 according to the Modified Ashworth Scale.
* Independent sitting balance (able to sit unsupported for at least 30 seconds).
* Presence of sufficient voluntary active movement in the lower extremity to permit exercise application.
* Ability to communicate.
* Willingness to participate in the study and provision of written informed consent.
Exclusion Criteria:
* Presence of hemispatial neglect.
* History of recurrent stroke.
* Presence of a psychiatric disorder.
* Presence of orthopedic, neurological, or cardiopulmonary conditions that would contraindicate the planned exercise protocols.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in quadriceps muscle thickness measured by ultrasonography