CompletedNot Applicable

Effect of 0° and 50° N-K Table Load Angles on Quadriceps Activation in Knee Osteoarthritis

Indonesia43 participantsStarted 2024-01-20

Plain-language summary

Knee osteoarthritis (OA) is a common degenerative joint disease that leads to pain, reduced mobility, and functional limitation. Quadriceps femoris weakness plays a significant role in disease progression and disability. Isotonic strengthening using the N-K Table allows adjustment of load angles to optimize muscle activation; however, the effect of different load angles on quadriceps activation in patients with knee osteoarthritis remains unclear. This study aims to compare quadriceps femoris activation at 0° and 50° N-K Table load angles in patients with knee osteoarthritis using surface electromyography (sEMG). A randomized cross-over experimental design is applied to determine whether adjusting the load angle improves maximum voluntary contraction (MVC) during isotonic knee extension exercise.

Who can participate

Age range

50 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with unilateral or bilateral knee osteoarthritis (OA), grade 2 or 3, in the subacute or chronic phase based on the criteria of the American College of Rheumatology (ACR) and Kellgren-Lawrence classification. * Female, aged 50-65 years, based on ACR diagnostic criteria. * Knee flexion-extension range of motion of at least 0-120 degrees. * Normal cognitive function as assessed using the Montreal Cognitive Assessment Indonesia Version (MoCA-INA) (score ≥26-30) Exclusion Criteria: * Knee joint instability due to ligament laxity in the cruciate or collateral ligaments obtained from physical examination (valgus/varus test and anterior/posterior drawer test) or previous supporting examination. * Presence of deformity in the form of genu varus, genu valgus, or genu recurvatum (Q angle 12-20°). * History of knee injury (fracture, ligament rupture, or meniscus) or having undergone knee surgery. * Pain or instability of the ankle joint obtained from physical examination. * Stroke or disorders of the central and peripheral nervous system. * Patients with metabolic diseases such as diabetes mellitus and heart disease or other autoimmune diseases based on medical records in unstable condition with pre-prandial capillary blood glucose ≠ 80-130 mg/dL or 1-2 hours post-prandial capillary blood glucose ≠ \<180 mg/dL, systolic blood pressure ≠ 90-140 mmHg and diastolic blood pressure ≠ 60-90 mmHg. * Pain durin loaded knee extension exercise greatetr than 3 on …

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Maximum Voluntary Contraction (MVC) of Quadriceps Femoris Muscles

Timeframe: Day 1

Trial details

NCT IDNCT07456254

SponsorIndonesia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-05

View on ClinicalTrials.gov More Knee Osteoarthritis trials