RecruitingNot Applicable

Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction

Egypt16 participantsStarted 2025-08-01

Plain-language summary

To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial

Who can participate

Age range13 Years – 20 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion).
✓. Fully erupted permanent teeth (except third molar).
✓. Age 13-20 patients.
✓. No previous orthodontic treatment.
✓. Good oral and general health.
✓. No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement.

Exclusion criteria

✕. Patients with impacted canines.
✕. Patients with severe crowding.
✕. Patients with untreated decay or any endodontic lesions.
✕. Patients with thyroid, parathyroid, or renal and liver disease.

What they're measuring

Rate of canine retraction

Timeframe: baseline to 3 months after initiation of canine retraction

Trial details

NCT IDNCT07455656

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-01

Contact for this trial

Mahmoud Elsaid Elsayed E Mahmoud Elsaid, BDS

+201003221008 mahmoud_elsaid@azhar.edu.eg

View on ClinicalTrials.gov More Malocclusions trials