Active — Not RecruitingPhase 2

Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel

China1,500 participantsStarted 2026-01-01

Plain-language summary

The objective is to compare the efficacy of SDF gel with that of NaF varnish in preventing carious lesions in preschool children when applied at half-yearly intervals over a 24-month period.

Who can participate

Age range3 Years – 5 Years

SexALL

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Inclusion Criteria: * generally healthy, with parental consents Exclusion Criteria: * uncooperative and difficult to manage, have major systemic diseases such as porphyria, or are on long-term medication such as anti-epileptic drugs.

What they're measuring

Caries prevention

Timeframe: The follow-up oral examinations will be conducted every 6 months for 24 months totally

Trial details

NCT IDNCT07455604

SponsorThe University of Hong Kong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-08-31

View on ClinicalTrials.gov More Early Childhood Caries (ECC) trials