Flow- Versus Volume-controlled Ventilation During Robot-assisted Laparoscopic Radical Prostatectomy (NCT07453810) | Clinical Trial Compass
CompletedNot Applicable
Flow- Versus Volume-controlled Ventilation During Robot-assisted Laparoscopic Radical Prostatectomy
Turkey (Türkiye)50 participantsStarted 2025-11-28
Plain-language summary
During robot-assisted laparoscopic radical prostatectomy (RALRP), patients are placed under general anesthesia and supported with mechanical ventilation. In this study, the effects of two different ventilatory strategies-flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV)-were compared. Using electrical impedance tomography (EIT) to provide real-time assessment of lung status and to guide individualized positive end-expiratory pressure (PEEP) settings, we investigated whether FCV offers superior oxygenation and improved respiratory system mechanics compared with VCV.
Who can participate
Age range
18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male patients aged 18 years or older
* American Society of Anesthesiologists physical status (ASA-PS) class I-III
* Scheduled for robot-assisted laparoscopic radical prostatectomy (RALRP)
* Provided written informed consent to participate in the study
Exclusion Criteria:
* Patients who declined to participate or withdrew consent
* Conversion from robot-assisted laparoscopic radical prostatectomy to open surgery
* Reoperation within 7 days postoperatively
* Chronic pulmonary disease
* Implanted cardiac devices
* Congestive heart failure New York Heart Association III/IV
* Severe haemodynamic instability after induction of anaesthesia
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The ratio of arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2)
Timeframe: During the intraoperative period at four predefined time points: after induction of general anesthesia (T1), after pneumoperitoneum and Trendelenburg positioning (T2), 60 minutes after T2 (T3), and before extubation (T4).