CompletedNot Applicable

Assessment of the Feasibility of Frozen Embryo Transfers in a Natural Cycle Among Obese Compared to Non-Obese Patients

France1,831 participantsStarted 2022-11-01

Plain-language summary

This retrospective study included 1,831 single blastocyst frozen embryo transfer (FET) cycles performed between November 1, 2022 and August 31, 2025. Three endometrial preparation protocols were used according to ovulatory status, cycle duration, and characteristics of previous FET cycles: modified natural cycle with ovulation trigger (mNC-FET) (n = 770), stimulated cycle FET (SC-FET) (n = 468), and hormone replacement therapy FET (HRT-FET) (n = 593). In natural cycles, if the predefined criteria for ovulation trigger were not met, the cycle was converted to a stimulated cycle. The aim of this study was to determine whether body mass index affects embryo transfer feasibility, reproductive outcomes, and cycle characteristics across different FET protocols.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Women aged ≥18 years at the time of frozen embryo transfer. Patients undergoing assisted reproductive technology (ART) with frozen embryo transfer (FET) using a natural, modified natural, stimulated, or hormone replacement therapy (HRT) protocol. Availability of body mass index (BMI) measurement prior to initiation of the treatment cycle.

What they're measuring

feasibility of embryo transfer

Timeframe: scheduled day of embryo transfer (Day 0 of planned FET cycle)

Trial details

NCT IDNCT07450300

SponsorClinique Mathilde

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-08-31

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