RecruitingNot Applicable

A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients

China200 participantsStarted 2026-03-20

Plain-language summary

This is a prospective, multicenter real-world study to describe the postoperative outcomes and quality of life, disease control and characteristics of patients who underwent surgery, as well as economic burden and post-operative treatment patterns in Chinese patients with CRSwNP recurrence.

Who can participate

SexALL

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Inclusion criteria

✓. Participant must be 16 years of age or older, at the time of signing the informed consent.
✓. Participants with a documented diagnosis of CRSwNP.
✓. Endoscopic nasal polypectomy is performed during the screening period.
✓. Voluntarily participate and sign the informed consent form as described in A 3.
✓. No history or current psychiatric disorders, with normal cognitive functions including understanding, expression, and orientation.

Exclusion criteria

✕. Any significant disease or disorder that the investigator believes may place the patient at risk or may affect the study results or the patient's ability to participate in the study.
✕. Currently participating in an interventional study.
✕. Patients who are unable to independently complete questionnaires due to language barriers or mental status.

What they're measuring

• The observed and change from baseline of Sino-Nasal Outcome Test (SNOT)-22 score at week-52

Timeframe: week0-52

• The observed and change from baseline of Modified Lund-Kennedy (MLK) score at week-52

Timeframe: week0-52

Trial details

NCT IDNCT07446738

SponsorAstraZeneca

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2027-08-30

Contact for this trial

AstraZeneca Clinical Study Information Center

1-877-240-9479 information.center@astrazeneca.com

View on ClinicalTrials.gov More Chronic Rhinosinusitis With Nasal Polyps trials