Sex-specific differences in neurological emergencies such as Status epilepticus (SE) remain understudied despite growing recognition of gender disparities in medicine. This study aimes to investigate sex-related differences in etiology, diagnostics, treatment, and outcomes among patients with SE. The investigators conducted a retrospective analysis of 779 patients treated with SE at Marburg University Hospital between 2011 and 2023.
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Age at SE Onset
Timeframe: Baseline (day 1)
Diagnosis of SE Subtype
Timeframe: During hospital stay, maximum 30 days
Semiology: Focal vs. Generalized
Timeframe: During hospital stay, maximum 30 days
Non-convulsive SE
Timeframe: During hospital stay, maximum 30 days
History of Epilepsy Prior to SE
Timeframe: Baseline (day 1)
Guideline-based Treatment of SE
Timeframe: During hospital stay, maximum 30 days
Intubation During Treatment of SE
Timeframe: During hospital stay, maximum 30 days
History of Epilepsy Surgery
Timeframe: Baseline (day 1)
Length of Hospital Stay
Timeframe: Up to 100 days
Availability of Brain MRI During Hospital Stay
Timeframe: During hospital stay, maximum 30 days
Time to Brain MRI After SE Onset
Timeframe: During hospital stay, maximum 30 days
EEG with SE Available
Timeframe: During hospital stay, maximum 30 days
EEG Control Available
Timeframe: From hospital stay through follow-up (up to study completion, an average of 1 year)
Functional Outcome at Discharge (mRS)
Timeframe: Through study completion, an average of 12 days
Discharge Destination
Timeframe: Through study completion, an average of 12 days
Survival After One Year
Timeframe: One year after SE onset
Total Costs of Hospital Stay
Timeframe: Through study completion, an average of 12 days
Antiseizure Medication (ASM) Use Prior to SE
Timeframe: Baseline (day 1)
Number of Distinct ASMs Prior to SE
Timeframe: Baseline (day 1)
Type of ASMs Used Prior to SE
Timeframe: Baseline (day 1)
Prehospital Benzodiazepine Use Before SE
Timeframe: Baseline (day 1)
Number of Distinct Prehospital Benzodiazepines
Timeframe: Baseline (day 1)
Type of Prehospital Benzodiazepines Used
Timeframe: Baseline (day 1)
ASM Use During SE Treatment
Timeframe: During hospital stay, maximum 30 days
Number of Distinct ASMs During SE
Timeframe: During hospital stay, maximum 30 days
Type of ASMs Used During SE
Timeframe: During hospital stay, maximum 30 days
In-hospital Benzodiazepine Use
Timeframe: During hospital stay, maximum 30 days
Number of Distinct In-hospital Benzodiazepines
Timeframe: During hospital stay, maximum 30 days
Type of In-hospital Benzodiazepines Used
Timeframe: During hospital stay, maximum 30 days