Not Yet RecruitingNot Applicable

Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease

South Korea470,000 participantsStarted 2026-02-28

Plain-language summary

Studies exploring the feasibility of drug-eluting balloon (DCB) in de-novo coronary lesions are limited. There are scarce data comparing DCB with drug-eluting stent (DES) in patients with high bleeding risk (HBR), a situation in which long-term maintenance of dual antiplatelet therapy (DAPT) is a clinical dilemma. This target trial emulation aims to compare clinical outcomes between DCB angioplasty and conventional DES implantation in de-novo coronary lesions in patients with coronary artery disease.

Who can participate

SexALL

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Inclusion Criteria: * Patients with coronary artery disease undergoing percutaneous coronary intervention * Used devices number less than three (relatively simple lesion) Exclusion Criteria: * Hybrid strategy (DCB and DES use) * Failed percutaneous coronary intervention * Previous revascularization procedure before index percutaneous coronary intervention

What they're measuring

Rates of MACCE (major adverse cardiac and cerebrovascular events)

Timeframe: 3 years after index procedure

Trial details

NCT IDNCT07442500

SponsorSamsung Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-30

View on ClinicalTrials.gov More Coronary Artery Disease trials