Not Yet RecruitingNot Applicable

Older Age and Generalization

United States360 participantsStarted 2026-06-01

Plain-language summary

The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences? Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses. Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria: * Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report) * Fluent in English (self-report) * Right-handed (self-report) * Cognitively healthy (self report verified by score \> 24 on Montreal Cognitive Assessment) * Self-reported normal or corrected-to-normal vision Exclusion Criteria: * Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease) * Self-reported uncontrolled hypertension, diabetes, or thyroid disorder * Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form) * Self-reported difficulty lying still on one's back for 1-2 hours

What they're measuring

Behavioral memory responses

Timeframe: Session 2 (experimental session)

Neural memory responses

Timeframe: Session 2 (experimental session)

Trial details

NCT IDNCT07440017

SponsorCaitlin Bowman

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-12-01

Contact for this trial

Caitlin Bowman, PhD

414-251-5010 bowman2@uwm.edu

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