CompletedPhase 2

A-PRF and CGF in Palatal Donor Site Healing

Turkey (Türkiye)45 participantsStarted 2020-11-01

Plain-language summary

The objective of this study was to compare and evaluate the effects of concentrated growth factor (CGF) and advanced platelet-rich fibrin (A-PRF) clot membranes on palatal epithelial wound healing and postoperative discomfort following free gingival graft (FGG) harvesting.

Who can participate

Age range18 Years – 55 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * at least 18 years old, * without systemic or periodontal diseases, * without medical contraindications to periodontal surgery * with full-mouth plaque control scores ≤ 20% * Gingival index scores ≤ 1 Exclusion Criteria: * smoking habits, * diabetes mellitus, * pregnancy or lactation, * removable upper denture, * regular medication that could interpose the healing process, undergoing bisphosphonate therapy, history of radiation therapy of the jaws, and follow-up consults

What they're measuring

Epithelialization

Timeframe: Baseline

Epithelialization

Timeframe: 1 week post-surgery

Epithelialization

Timeframe: 2 week post-surgery

Epithelialization

Timeframe: 3 week post-surgery

Epithelialization

Timeframe: 4 week post-surgery

Pain perception

Timeframe: Baseline

Pain perception

Timeframe: 1st day after surgery

Pain perception

Timeframe: 2nd day after surgery

Pain perception

Timeframe: 3th day after surgery

Trial details

NCT IDNCT07439068

SponsorOrdu University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-30

View on ClinicalTrials.gov More Free Gingival Graft trials