Not Yet RecruitingNot Applicable

Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study

Ukraine150 participantsStarted 2026-03-24

Plain-language summary

Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue. This prospective cohort study aims to determine whether early ultrasound features of scars and nerves predict persistent clinically significant scar pain at 3 and 6 months. Ultrasound measures include scar thickness, echogenicity, Power Doppler vascularity, dynamic adhesion (gliding) assessment, and ultrasound signs of nerve involvement ("US-nerve positive"). Clinical outcomes include pain intensity (NRS), neuropathic pain screening (DN4), and functional interference.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥18 years * Burn injury with clinically formed scar * Enrollment 2-12 weeks after injury * Scar located on extremities, chest wall, or neck * Ability to provide written informed consent Exclusion Criteria: * Severe cognitive impairment preventing valid questionnaires * Hemodynamic instability or inability to complete baseline evaluation * Active systemic infection (enrollment deferred until stable) * Pre-existing chronic pain condition unrelated to burn scar that would confound outcomes (investigator judgment)

What they're measuring

Persistent clinically significant scar pain

Timeframe: 3 mounth

Trial details

NCT IDNCT07438769

SponsorUkrainian Society of Regional Anesthesia and Pain Therapy

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-05-23

Contact for this trial

Dmytro Dmytriiev, PhD.Professor

+380674309449 mddmytriiev@gmail.com

View on ClinicalTrials.gov More Burn Scar Pain trials