CompletedNot Applicable

Comparative Effects of MIIT With CT In Post-MVR Surgery Patients

Pakistan56 participantsStarted 2024-02-10

Plain-language summary

Mitral Valve Replacement (MVR) surgery is commonly performed to treat patients with severe mitral valve diseases, such as mitral stenosis or regurgitation. Patients after mitral valve replacement surgery often experience muscular weakness ,fatigue and reduced functional capacity due to the surgical procedure and the time period of post-operative recovery. A structured exercise program helps rebuild strength and regain mobility, allowing patients to perform daily activities with greater ease and independence. Moderate-intensity interval training (MIIT) with continuous training is crucial for patients after mitral valve replacement (MVR) surgery, as it significantly enhances cardiopulmonary fitness. But the comparative effects of Moderate-intensity interval training (MIIT) with continuous training have not been well documented and practiced in Pakistan. The study aims to determine the comparative effects of Moderate-intensity interval training (MIIT) and moderate continuous training on physical capacity, cardiac efficiency, pulmonary function, and quality of life after mitral valve surgery. The study will be single blinded, randomized clinical trial. Based on inclusion and exclusion criteria patients were divided into two groups. The MIIT group and MICT group. The study was of 12 weeks session, 3 sessions per week (3 months). The data was analyzed through SPSS-23. Outcome measures were pulmonary function tests (spirometery), 6-Minute Walk Test (6MWT) and quality of life assessed through IPAQ. Cardiac efficiencywas measured by evaluating heart rate recovery, exercise tolerance, and cardiac output.

Who can participate

Age range40 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Both male and female age 40-60 years * Hemodynamically stable heart rate and blood pressure * Patients 4-8 weeks post-mitral valve replacement (MVR) surgery * Stable medical condition for MIIT * Able to walk independently for at least 5 minutes without assistance * Stable pulmonary function without severe pulmonary complications (e.g., severe chronic obstructive pulmonary disease). * No ongoing respiratory infections or severe heart failure. Exclusion Criteria: * Presence of unstable angina, severe heart failure (ejection fraction \< 30%), or other significant cardiac arrhythmias that contraindicate exercise. * Conditions that limit mobility or the ability to perform exercises safely (e.g., severe arthritis, recent fractures, or neuromuscular diseases). * Patients with severe respiratory conditions (e.g., severe asthma or COPD exacerbation) that would limit participation in exercise. * Other serious co-morbidities (e.g., uncontrolled diabetes, severe hypertension, renal failure) that may impact safe participation in exercise. * Participation in any other structured exercise program

What they're measuring

6MWT

Timeframe: 12 week

Digital Spirometer

Timeframe: 12 week

VO₂ Peak

Timeframe: 12 weeks

IPAQ

Timeframe: 12 weeks

Trial details

NCT IDNCT07438717

SponsorRiphah International University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-05