Not Yet RecruitingNot Applicable

Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain

60 participantsStarted 2026-02-15

Plain-language summary

Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the combination of PIP block and ESPB in patients undergoing modified radical mastectomy for reducing acute and chronic post mastectomy pain

Who can participate

Age range18 Years – 65 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients aged ≥18 years. * American Society of Anesthesiologists (ASA) class I-III. * Scheduled for unilateral modified radical mastectomy. Exclusion Criteria: * Known allergy to local anesthetics or magnesium. * Coagulopathy or anticoagulant therapy. * Local infection at injection site. * Body mass index (BMI) ≥ 40 kg/m2. * Chronic opioid use or chronic pain disorders. * Neurological or psychiatric disorders affect pain perception. * Severe hepatic or renal impairment. * Pregnancy. * Lactation.

What they're measuring

Time to first rescue analgesia.

Timeframe: 24 hours postoperatively

Trial details

NCT IDNCT07438366

SponsorSouth Egypt Cancer Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11-01

Contact for this trial

mohamed fa abd elhamed, lecturer

01015249890 m.farghaly.na@gmail.com

View on ClinicalTrials.gov More Post-mastectomy Pain Syndrome trials