Not Yet RecruitingNot Applicable

Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy

100 participantsStarted 2026-02-15

Plain-language summary

Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients undergoing modified radical mastectomy. Study Endpoints Primary Endpoints: Total intravenous opioid consumption during the first 24 hours following surgery. Secondary Endpoints: Postoperative analgesia, 24 hours after surgery, assessed using the Visual Analog Scale (VAS) and time to first analgesic request.

Who can participate

Age range30 Years – 75 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients aged 30 to 75 years diagnosed with non-metastatic breast cancer and scheduled for modified radical mastectomy. * ASA, I-III and NYHA, I-II. * Written informed consent. Exclusion Criteria: * ASA physical status \>III and NYHA \>II, * body mass index \>40 kg/m2, * pregnant women, * Patients with organ failure or coagulation disorders. * Allergy to local anesthetics or magnesium sulfate * Contraindications as local infection * History of chronic pain or opioid use . * Unwilling to participate in the study

What they're measuring

intravenous opioid consumption

Timeframe: 24 hours postoperatively

Trial details

NCT IDNCT07434232

SponsorSouth Egypt Cancer Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-01

Contact for this trial

mohamed fa abd elhamed, lecture

01015249890 m.farghaly.na@gmail.com

View on ClinicalTrials.gov More Modified Radical Mastectomy trials