Mammogram Pretreatment With Ulipristal Acetate

Inclusion Criteria: * Participant or legally authorized representative (LAR) must provide written informed consent before any study-specific procedures or interventions are performed * Ages 18-50 years. The maximum age cut off is due to the intervention only applying to premenopausal physiology only * Assigned female at birth with at least one ovary in situ. Members of all races and ethnic groups will be included * Presenting for a screening mammogram * Has an antecedent mammogram within 24 months with a Breast Imaging Reporting and Data System (BI-RADS) breast composition score of Category D (extremely dense) for which images are available for analysis * Report no history of breast cancer or symptoms concerning for breast cancer such as a self-palpated mass * Reasonably assumed to be premenopausal by history of regular menses. For individuals who do not menstruate (due to hysterectomy or endometrial ablation), premenopausal status will be determined clinically by the absence of symptoms of menopause including weekly hot flashes which is consistent with clinical care Exclusion Criteria: * Having a mammogram as part of a diagnostic process * Current breast implants in one or both breasts * Pregnant, less than 1 year postpartum or breastfeeding within last 6 months at the time of their antecedent mammogram or their current mammogram. This exclusion is due to known changes in mammograms during pregnancy and postpartum that would preclude comparative analyses * Using hormonal …