This study adopted a multicenter, randomized, double-blind, placebo-controlled phase II/III operation seamless adaptive design, aiming to evaluate the efficacy, safety and tolerability of CMS-D001 tablets in the treatment of patients with moderate to severe plaque psoriasis. The trial consists of two parts, including the Phase II clinical research stage and the Phase III clinical research stage.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Phase â…¡:Number of participants achieving at least 75% improvement in Psoriasis Area and Severity Index (PASI 75)
Timeframe: At week 12
Phase â…¢:Number of participants achieving at least 75% improvement in Psoriasis Area and Severity Index (PASI 75)
Timeframe: At week 16
Phase â…¢:Number of participants achieving a Physician Global Assessment (PGA) score of 0 (clear) or 1 (almost clear) (PGA-TS)
Timeframe: At week 16