Children's Health, Respiratory Inflammation and Short-term Air Pollution (NCT07431021) | Clinical Trial Compass
RecruitingNot Applicable
Children's Health, Respiratory Inflammation and Short-term Air Pollution
United Kingdom330 participantsStarted 2025-10-20
Plain-language summary
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
Who can participate
Age range
7 Years – 11 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Attending schools in Central and East London that have been recruited to the study
Exclusion Criteria:
* Not able to engage with PE lessons on safety grounds, reported by their parents.
* Children with learning or physical disabilities sufficient for them to be unable to give informed assent to the study, or to carry out study procedures
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is measuring airway resistance in children using something called oscillometry — how is that test done, and is it safe and comfortable for a child with acute asthma?
2Since this trial is labeled 'Phase NA,' it sounds more like an observational or measurement study than a treatment trial — can you help me understand whether my child would receive any different treatment, or is this purely about collecting data on how air pollution affects their breathing?
3The study links short-term air pollution exposure to respiratory inflammation in children with asthma — given where we live and my child's current asthma control, do you think our local air quality makes this study especially relevant for us?
4What would my child actually need to do as a participant — how many visits, how often, and would any of that interfere with their normal asthma care or school routine?
5Are there any standard asthma management steps or environmental controls you'd recommend we try first, and would participating in this study complement or complicate those efforts?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
"Airway resistance" measured by Oscillometry at R5