CompletedNot Applicable

Nicotinamide Adenine Dinucleotide Responses to a Nutritional Supplement

United States29 participantsStarted 2026-02-17

Plain-language summary

The objective of this study is to evaluate nicotinamide adenine dinucleotide (NAD+) in response to a proprietary nutritional supplement in generally healthy adults, compared to placebo.

Who can participate

Age range

45 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Males and females, ≥45 to ≤65 years of age
. BMI ≥18.5 and \<30.0 kg/m2
. Ambulatory and currently free of injury or other physical impairment that hinders mobility.
. Willing to use personal smart phone with operating system (Android version 12.0 or newer; iOS version 16 or newer).
. Willingness to maintain current skin care regimen and avoid any skin-related medical procedures.
. Willing to adhere to all study procedures, including lifestyle considerations and sign forms providing informed consent to participate in the study and authorization to release relevant protected health information to the Clinical Investigator.

Exclusion criteria

. Is currently following, or planning to be on, a weight loss regimen.
. Weight loss or gain \>4.5 kg.
. History of gastrointestinal surgery for weight reducing purposes.
. History of an eating disorder (e.g., anorexia nervosa or bulimia nervosa, binge eating) at the discretion of the Clinical Investigator.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Nicotinamide adenine dinucleotide response in whole blood

Timeframe: Baseline to Day 14

Trial details

NCT IDNCT07428889

SponsorShaklee Corporation

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-04-05

View on ClinicalTrials.gov More Healthy Adult trials