By InvitationNot Applicable

Feasibility of Intradialytic Monitoring During CKRT

United States30 participantsStarted 2026-03-17

Plain-language summary

This is a pilot observational cohort study to understand whether advanced monitoring techniques can be applied during continuous kidney replacement therapy (CKRT), which is the most common form of dialytic therapy provided in critically ill patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients who have been admitted to the Medical ICU or Cardiothoracic ICU at the Hospital of the University of Pennsylvania (HUP).
✓. Patients who have been prescribed continuous venovenous hemodialysis (CVVHD) or Continuous Veno-Venous Hemofiltration (CVVH), the predominant modalities of continuous kidney replacement therapy (CKRT) at HUP.
✓. Patients who have central venous catheters placed in either the left or right internal jugular veins.

Exclusion criteria

✕. Patients who are prescribed other forms of CKRT, namely continuous venovenous hemofiltration (CVVH), slow continuous ultrafiltration (SCUF), or prolonged intermittent kidney replacement therapy (PIKRT).
✕. Patients who have femoral vein dialysis catheters placed.
✕. Patients who cannot provide consent or have a legal proxy to provide consent.

What they're measuring

Accuracy (% deviation) of hematocrit measured by CLM (Hct CLM) and hematocrit as measured by complete blood count (Hct CBC).

Timeframe: 48-hour dialysis treatment

Trial details

NCT IDNCT07428395

SponsorUniversity of Pennsylvania

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-03

View on ClinicalTrials.gov More Acute Kidney Injury trials