Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder

Inclusion Criteria: For all participants: * Participants must be capable of giving informed consent. * Participants must be able to understand and follow the instructions in the project. * Access to a smartphone and ability to use a smartphone and actimeter. For patients with bipolar disorder * Confirmed diagnosis of bipolar disorder (type 1 or type 2) according to ICD-10 after completion of an assessment at a psychiatric clinic in the Stockholm Region. * Patients must be euthymic (stable and free from affective episodes) at the time of inclusion. * Consent for the research team to access relevant clinical data from patient records. For patients with recurrent depression * Confirmed diagnosis of recurrent depression according to ICD-10 after completion of an assessment at a psychiatric clinic in Region Stockholm. * Patients must have been referred for diagnostic assessment with the question of bipolar disorder. * Patients must be euthymic (stable and free from affective episodes) at the time of inclusion. Exclusion Criteria: Common to all participants: * Active substance abuse or dependence (alcohol or other substances). * Neurological disease or cognitive impairment that may affect study results or compliance with study procedures. * Inability to use a smartphone and smartwatch as required by the study. * Inability to provide valid informed consent. * Inability to understand and follow the study instructions (good knowledge of Swedish is required). For adults witho…