The Role of Priors in Hallucinatory Perception in Parkinson's Disease (NCT07427498) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Role of Priors in Hallucinatory Perception in Parkinson's Disease
France60 participantsStarted 2026-03
Plain-language summary
The goal of this observational study is to better understand the mechanisms of hallucinations in patients with Parkinson's disease. The main question it aims to answer is:
Do prior expectations increase the rate of false perceptions during a visual stimulus detection task more in Parkinson's disease patients with visual hallucinations compared to those without?
Participants will undertake a computer task involving face detection and a battery of neuropsychological tests.
Who can participate
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults diagnosed with Parkinson's disease (with or without visual hallucinations) or healthy volunteers.
* Age 18 - 85 years.
* Consent to participate.
Exclusion Criteria:
* Currently participating in another clinical or therapeutic trial involving the testing of a drug treatment.
* Inability to perform cognitive tests due to:
Non-psychiatric (somatic) conditions likely to affect cognitive abilities. Peripheral sensory or motor deficits. Acute clinical conditions (e.g., agitation, impaired consciousness).
* Diagnosis of dementia.
* Individuals covered by Articles L1121-5 to L1121-8 of the French Public Health Code (Code de la Santé Publique), including:
Pregnant women, women in labor, or breastfeeding mothers. Individuals deprived of liberty by judicial or administrative decision. Individuals receiving psychiatric care under Articles L. 3212-1 and L. 3213-1 (excluding those covered by Article L. 1121-8).
Individuals admitted to a healthcare or social institution for purposes other than research.
Minors or adults under legal guardianship or unable to express consent.
\- Individuals with a hierarchical relationship to any professional involved in the study.
Only for healthy volunteers:
\- Personal history of diagnosed neurological disorders.
Post-Inclusion Exclusion:
\- Participants included in the study but found to have a MoCA score below 24 will be excluded from the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Effect of Prior Expectations on False Alarm Rates in Parkinson's Disease Patients With and Without Visual Hallucinations