Active — Not RecruitingNot Applicable

Evaluate the Effect of Fluoride-Releasing Composite Resin on Prevention of White Spot Lesions During Clear Aligner Therapy

Egypt24 participantsStarted 2025-08-01

Plain-language summary

Aim of this study: evaluate the effect of fluoride-releasing composite resin as attachments on prevention of white spot lesions. Material and methods: Type: Prospective, randomized split mouth controlled study. Interventions: Intervention Group (Experimental Side): •Application of fluoride-releasing composite Control Group (Control Side): •Application of conventional composite Outcome Measures: Primary Outcome: Incidence and Severity of White Spot Lesions Secondary Outcomes: 1. Periodontal Ligament (PDL) Health 2. Gingival Bleeding and Inflammation

Who can participate

Age range16 Years – 24 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 16-24 years. * Good general and oral health. * Mild dental crowding per arch (≤ 4 mm). Exclusion Criteria: * Systemic conditions affecting tooth movement (e.g., diabetes, bone disorders). * Patients with Cleft lip and palate. * Previous orthodontic treatment. * Dental fluorosis. * Hypocalcified teeth or visible demineralization.

What they're measuring

White Spot Lesions

Timeframe: six months

Trial details

NCT IDNCT07426432

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-01

View on ClinicalTrials.gov More White Spot Lesions trials