RecruitingNot Applicable

Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers

Germany48 participantsStarted 2026-06-01

Plain-language summary

The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff, comparing employees with night shifts to employees without night shifts.

Who can participate

Age range

18 Years – 67 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged between 18 and 67 * Male or female * Currently employed * Body-Mass-Index (BMI) \<40 kg/m2 * Working hours ≥28 hours/week * Employees working night shifts (group A): (1) Working night shifts for \>1 year, (2) at least two night shifts within the 2-week observation period * Employees not working night shifts (group B): No night shifts for \>1 year * Capable of giving consent * Health insurance * Good knowledge of German Exclusion Criteria: * Pregnancy and breastfeeding * Special diets, e.g. intermittent fasting * Severe acute or chronic illnesses, e.g. type 1 diabetes mellitus, liver or kidney disease, heart attack within the last 6 months, stroke or systemic infections, current cancer or cancer within the last 2 years * Bariatric surgery * Hereditary or acquired blood clotting disorders * Severe mental illnesses, e.g. depression, addiction or eating disorders (individual assessment by study staff, if necessary after consultation with a doctor) * Holiday in a different time zone (≥ 2 hours time difference) one month before study participation or within the 2-week observation phase * Participation in another study that could influence the results of the current study * Special drug therapies that could influence the study results (individual assessment by study staff, if necessary after consultation with a physician) * Physical or mental difficulties in understanding and following instructions from study staff

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mean 24-hour glucose levels and mean night glucose levels

Timeframe: 2 weeks

Trial details

NCT IDNCT07426211

SponsorOlga Ramich (formerly Pivovarova)

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-01

Contact for this trial

Olga Ramich, Prof. Dr.

+49 33200 882749 olga.ramich@dife.de

View on ClinicalTrials.gov More Chronodisruption trials

Who can participate

Age range

18 Years – 67 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.