Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism. (NCT07426172) | Clinical Trial Compass
RecruitingNot Applicable
Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
Spain24 participantsStarted 2026-01-20
Plain-language summary
The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance. The investigators will conduct an intervention study in which blood lactate levels will be elevated via intravenous infusion of sodium lactate. State of the art metabolic assessment using stable isotopes and indirect calorimetry will be used to study alterations in fat and carbohydrate metabolism.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Men and women
* \>18 years of age
* Women non-pregnant or taking contraceptive medication
* Physically active according to WHO's guidelines
* Metabolic syndrome as IDF 2009 criteria (Alberti et al., Circulation)
* Written and verbal consent to participation
Exclusion Criteria:
* Chronic illness that prevents them from exercising
* Affected blood samples at screening, as assessed by the PI
* Assessed as unsuitable by PI
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Lipolysis rate at rest, exercise and OGTT when blood lactate is elevated in MH individuals
Timeframe: through study completion, an average of 2 years
2
Effect of Na-Lactate on glucose tolerance to an oral load
Timeframe: through study completion, an average of 2 years