Not Yet RecruitingNot Applicable

Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns

France1,600 participantsStarted 2026-03

Plain-language summary

Currently in France, screening for congenital hypothyroidism (CH) in premature infants is done by a single TSH assay on filter paper. However, European recommendations advise repeating the assay within the first month of life. Our primary objective is to estimate the incidence of CH in preterm infants under 32 weeks of gestational age by applying the European recommendations.

Who can participate

Age range23 Weeks – 32 Weeks

SexALL

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Inclusion Criteria: * Newborns born prematurely between 23 and 32 weeks of gestational age (up to 31 weeks and 6 days), both female and male, of all ethnic origins, regardless of birth weight, and including all other pathologies. * Newborns whose parents have given their non-opposition consent. Exclusion Criteria: * Newborns born who leave the region before day 15. * Newborns who die before 15 days of age. * Newborns whose parents are not affiliated with the social security system.

What they're measuring

Annual incidence of congenital hypothyroidism among premature infants born before 32 weeks of gestational age

Timeframe: From birth to Day 15 of life

Trial details

NCT IDNCT07425028

SponsorUniversity Hospital, Lille

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-03

Contact for this trial

Christine LEFEVRE, MD

03.20.44.50.70 christine.lefevre@chu-lille.fr

View on ClinicalTrials.gov More Congenital Hypothyroidism trials