Active — Not RecruitingNot Applicable

Pilot Study of a Brain Health Program in Senior Centers

United States60 participantsStarted 2026-01-06

Plain-language summary

The investigators will evaluate a brain health programs in older adults with subjective cognitive decline. The primary aim of the study is to determine the credibility, expectancy, feasibility, acceptability, appropriateness, fidelity, and satisfaction of the program delivered in the senior centers.

Who can participate

Age range

50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged ≥ 50 * Subjective cognitive decline (SCD; e.g., forgetting information, getting lost, and repeating oneself) * Able to self-identify at least 1 modifiable lifestyle risk factors for dementia to change during the program (physically inactive, poor sleep, non-adherence to Mediterranean diet, alcohol use, tobacco use, socially isolated or lonely, mental inactivity) * Absence of significant cognitive impairment (assessed using Short Blessed Test71 ≤ 9) * Self-reported English proficiency/literacy * Ability and willingness to participate and complete all study-related activities Exclusion Criteria: * Dementia or other neurodegenerative disease per patient self-report or disclosure * Psychosis, uncontrolled schizophrenia or schizoaffective disorder, uncontrolled bipolar disorder, or uncontrolled substance dependence/abuse * Active self-report of suicidal ideation / high risk of suicide * Serious medical illness expected to worsen during the study * Self-reported safety issues with initiating lifestyle change

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This study is focused on preventing dementia and reducing memory loss in people at senior centers — given my current memory concerns and lifestyle, do you think I'm the kind of person this program was designed for?
2Since this trial is already active and not recruiting new participants, is there any chance of getting on a waitlist, or should we be looking for a similar program that's still enrolling?
3The study is measuring whether people actually complete the program and whether they're satisfied with it — what does that tell us about how much is actually known yet about whether it improves memory or reduces dementia risk?
4This program targets sedentary behavior and physical activity as lifestyle risk factors — are there evidence-based lifestyle changes you'd recommend I start now, regardless of whether I join a trial like this?
5Since this is a pilot study with no specific drug or medical procedure involved, how does its 'NA' phase status affect how I should weigh it against other options, including just working with you directly on a brain health plan?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Rates of Treatment Completion

Timeframe: 8 Weeks

Client Satisfaction Questionnaire

Timeframe: 8 Weeks

Trial details

NCT IDNCT07424443

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-01

View on ClinicalTrials.gov More Memory Loss (Excluding Dementia) trials