CompletedNot Applicable

Integrated vs Manual Endotracheal Tube Cuff Pressure Monitoring and Ventilator-Associated Pneumonia

Slovenia40 participantsStarted 2021-12-01

Plain-language summary

Ventilator-associated pneumonia (VAP) is a frequent complication in mechanically ventilated patients in intensive care unit (ICU). This prospective cohort study compares the incidence of VAP between patients whose endotracheal tube cuff pressure was controlled continuously using an integrated ventilator cuff-pressure control system versus intermittent manual manometric monitoring performed by staff.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ICU admission after severe head injury * Endotracheal intubation and invasive mechanical ventilation * Expected mechanical ventilation \>48-72 hours (recommended to add for PRS clarity) * Informed consent from family/legal representative Exclusion Criteria: * Pneumonia/VAP diagnosed within the first 48 hours of ICU admission/ventilation * Removal or replacement of endotracheal tube during observation window * Tracheotomy performed within 7 days of admission * Missing required assessments/results (optional to include as operational exclusion)

What they're measuring

Incidence of ventilator-associated pneumonia (VAP)

Timeframe: From Day 3 to Day 7 (assessed on days 3, and 7; VAP defined as onset >48-72 hours after initiation of invasive ventilation)

Trial details

NCT IDNCT07423208

SponsorUniversity Medical Centre Ljubljana

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-01-07

View on ClinicalTrials.gov More Ventilator Associated Pneumonia ( VAP) trials