CompletedNot Applicable

Assessment of Licorice Extract as an Adjunctive Therapy to Mechanical Debridement in Stage II Periodontitis

Egypt50 participantsStarted 2025-02-01

Plain-language summary

To assess the clinical effectiveness of the locally delivered licorice extract as an adjunctive therapy to mechanical debridement in stage II periodontitis patients. To assess the impact of the locally delivered licorice extract as an adjunctive therapy to mechanical debridement on the level of interleukin-6 in the GCF in stage II periodontitis patients .

Who can participate

Age range30 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with Stage II Periodontitis (mainly horizontal bone loss with maximum probing depth ≤ 5 mm and with 3-4 mm clinical attachment loss). * Age range (30 - 50) years. * Good compliance with the plaque control instructions following initial therapy. * Availability for follow up and maintenance program. Exclusion Criteria: * Smoking. * Systemic diseases which could influence the outcome of the therapy (According to Cornell Medical Index-Health Questionnaire). * Pregnant and lactating females. * Vulnerable groups of patients' e.g (prisoners, disabled patients and decisionally impaired individuals).

What they're measuring

To assess the clinical effectiveness of the locally delivered licorice extract gel as an adjunctive therapy to mechanical debridement in Stage II periodontitis patients

Timeframe: samples will be collected at Base line then after 3 months by using periopaper strips

Trial details

NCT IDNCT07422883

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-15

View on ClinicalTrials.gov More Interleukin 6 trials